⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7485551 | 0.93 | ALDH1A1 (0.37) | — | |
| SCHEMBL4333124 | 0.93 | ALDH1A1 (0.44) | — | |
| SCHEMBL6322740 | 0.91 | ALDH1A1 (0.36) | — | |
| SCHEMBL4325752 | 0.91 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL7991224 | 0.91 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL4954390 | 0.91 | ALDH1A1 (0.36) | — | |
| SCHEMBL9214644 | 0.91 | ALDH1A1 (0.36) | — | |
| SCHEMBL9202745 | 0.91 | ALDH1A1 (0.36) | — | |
| SCHEMBL7991219 | 0.91 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL4953613 | 0.91 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101715451-A | Novel pyridopyrazine derivatives, process for their preparation and their use | AETERNA ZENTARIS GMBH | 2010-05-26 | — | — | CN | claimed |
| US-10201617-B2 | 3-substituted piperidine-2, 6-diones and non-covalent complexes with albumin | ZHUHAI BEIHAI BIOTECH CO., LTD. (CN) | 2019-02-12 | — | — | US | disclosed |
| US-20170319708-A1 | 3-Substituted Piperidine-2, 6-Diones and Non-Covalent Complexes with Albumin | ZHUHAI BEIHAI BIOTECH CO., LTD. (CN) | 2017-11-09 | — | — | US | disclosed |
| CN-101715451-B | Novel pyridopyrazine derivatives, process for their preparation and their use | AETERNA ZENTARIS GMBH | 2013-07-31 | — | — | CN | disclosed |
| CN-101715451-A | Novel pyridopyrazine derivatives, process for their preparation and their use | AETERNA ZENTARIS GMBH | 2010-05-26 | — | — | CN | disclosed |
| EP-0742218-B1 | PYRROLOPYRIDAZINE DERIVATIVE | SANKYO CO (JP) | 2002-12-04 | — | — | EP | disclosed |
| US-6277790-B1 | APPLYING PLANTS, SEEDS, SOILS OR ENVIRONMENT | BASF AKTIENGESELLSCHAFT (DE) | 2001-08-21 | — | — | US | disclosed |
| EP-1003741-A1 | SUBSTITUTED HERBICIDE TETRAZOLINONECARBOXYLIC ACID AMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-31 | — | — | EP | disclosed |
| US-6063782-A | Pyrrolopyridazine derivatives | SANKYO COMPANY, LIMITED (JP) | 2000-05-16 | — | — | US | disclosed |
| WO-1999007702-A1 | SUBSTITUTED HERBICIDE TETRAZOLINONECARBOXYLIC ACID AMIDES | BASF AKTIENGESELLSCHAFT (DE) | 1999-02-18 | — | — | WO | disclosed |
| EP-0742218-A1 | PYRROLOPYRIDAZINE DERIVATIVE | SANKYO COMPANY LIMITED (JP) | 1996-11-13 | — | — | EP | disclosed |