Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4954390 | 1.00 | ALDH1A1 (0.36) | ALDH1A1ALOX15SMN1; SMN2USP2NPSR1 | |
| SCHEMBL4953613 | 1.00 | ALDH1A1 (0.36) | ALDH1A1ALOX15SMN1; SMN2USP2NPSR1 | |
| SCHEMBL6322740 | 1.00 | ALDH1A1 (0.36) | ALDH1A1ALOX15SMN1; SMN2USP2NPSR1 | |
| SCHEMBL9202745 | 1.00 | ALDH1A1 (0.36) | ALDH1A1ALOX15SMN1; SMN2USP2NPSR1 | |
| SCHEMBL7485551 | 0.98 | ALDH1A1 (0.37) | ALDH1A1ALOX15SMN1; SMN2USP2NPSR1 | |
| SCHEMBL4953807 | 0.94 | ALDH1A1 (0.42) | ALDH1A1ALOX15SMN1; SMN2USP2NPSR1 | |
| SCHEMBL4325783 | 0.94 | ALDH1A1 (0.42) | ALDH1A1ALOX15SMN1; SMN2USP2NPSR1 | |
| SCHEMBL791252 | 0.92 | ALDH1A1 (0.43) | ALDH1A1ALOX15SMN1; SMN2USP2NPSR1 | |
| SCHEMBL7485263 | 0.91 | — | — | |
| SCHEMBL4337073 | 0.90 | SMN1; SMN2 (0.42) | ALDH1A1ALOX15SMN1; SMN2USP2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |