SCHEMBL4333124

SCHEMBL4333124

[CH2]CCCC1=CCCCC1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.44
ALOX15 P16050 2/20 0.44
SMN1; SMN2 Q16637 3/20 0.41
USP2 O75604 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
PKM P14618 1/20 0.40
TAAR1 Q96RJ0 1/20 0.39
RAB9A P51151 4/20 0.38
NPC1 O15118 3/20 0.38
LMNA P02545 1/20 0.38
HTT P42858 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
KDM4E B2RXH2 1/20 0.37
MAPT P10636 1/20 0.37
ALOX12 P18054 1/20 0.37
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7991224 0.98 SMN1; SMN2 (0.44) ALDH1A1ALOX15SMN1; SMN2USP2NPSR1
SCHEMBL4325752 0.98 SMN1; SMN2 (0.44) ALDH1A1ALOX15SMN1; SMN2USP2NPSR1
SCHEMBL7991219 0.98 SMN1; SMN2 (0.44) ALDH1A1ALOX15SMN1; SMN2USP2NPSR1
SCHEMBL791252 0.94 ALDH1A1 (0.43) ALDH1A1ALOX15SMN1; SMN2USP2NPSR1
SCHEMBL7485263 0.93
SCHEMBL4337065 0.92 SMN1; SMN2 (0.42) ALDH1A1ALOX15SMN1; SMN2USP2NPSR1
SCHEMBL4325783 0.92 ALDH1A1 (0.42) ALDH1A1ALOX15SMN1; SMN2USP2NPSR1
SCHEMBL4953807 0.92 ALDH1A1 (0.42) ALDH1A1ALOX15SMN1; SMN2USP2NPSR1
SCHEMBL4337073 0.92 SMN1; SMN2 (0.42) ALDH1A1ALOX15SMN1; SMN2USP2NPSR1
SCHEMBL7485551 0.87 ALDH1A1 (0.37) ALDH1A1ALOX15SMN1; SMN2USP2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0179619-A1 Heterocyclic amides ICI AMERICAS INC. (US) 1986-04-30 EP claimed
EP-0003663-A2 Amino-substituted phenyl and heteroaryl compounds, process for their preparation and pharmaceutical compositions containing them AMERICAN CYANAMID COMPANY (US) 1979-08-22 EP claimed
WO-2024106539-A1 LIGAND CONJUGATE SUBSTANCE, NUCLEIC ACID CONTAINING SAME, AND USE THEREOF 株式会社ボナック 2024-05-23 WO disclosed
US-20230357767-A1 NOVEL NUCLEIC ACID MOLECULE INHIBITING EXPRESSION OF TARGET GENE BONAC CORPORATION (JP) 2023-11-09 US disclosed
EP-4206325-A1 NOVEL NUCLEIC ACID MOLECULE INHIBITING EXPRESSION OF TARGET GENE BONAC CORPORATION (JP) 2023-07-05 EP disclosed
US-20230183283-A1 NOVEL GLYCOSIDE COMPOUND AND PRODUCTION METHOD THEREFOR BONAC CORPORATION (JP) 2023-06-15 US disclosed
EP-3527578-A1 NOVEL GLYCOSIDE COMPOUND AND PRODUCTION METHOD THEREFOR Bonac Corporation (JP) 2019-08-21 EP disclosed
US-10377788-B2 Method for producing glycoside compounds BONAC CORPORATION (JP) 2019-08-13 US disclosed
EP-3301103-A1 METHOD FOR PRODUCING GLYCOSIDE COMPOUNDS BONAC CORPORATION (JP) 2018-04-04 EP disclosed
US-20180079768-A1 METHOD FOR PRODUCING GLYCOSIDE COMPOUNDS BONAC CORPORATION (JP) 2018-03-22 US disclosed
US-9222032-B2 Composition and methods for improved fuel production MISSISSIPPI STATE UNIVERSITY (US) 2015-12-29 US disclosed
EP-0742218-A1 PYRROLOPYRIDAZINE DERIVATIVE SANKYO COMPANY LIMITED (JP) 1996-11-13 EP disclosed
EP-0421441-B1 Pantothenic acid derivatives FUJIREBIO KK (JP) 1995-01-25 EP disclosed
US-5120738-A Cardiovascular disorders FUJIREBIO INC. (JP) 1992-06-09 US disclosed
EP-0421441-A2 Pantothenic acid derivatives FUJIREBIO INC. (JP) 1991-04-10 EP disclosed
EP-0227241-A2 Medicinal indole and indazole keto sulphone derivatives ZENECA INC. (US) 1987-07-01 EP disclosed
EP-0179619-A1 Heterocyclic amides ICI AMERICAS INC. (US) 1986-04-30 EP disclosed
US-4333940-A Ring-fluorinated 4-(monosubstituted-amino) phenyl compounds in inhibiting atherosclerotic lesion development AMERICAN CYANAMID COMPANY (US) 1982-06-08 US disclosed
US-4243609-A ANTILIPEMIC AGENTS, ANTIATHEROSCLEROTIC AGENTS AMERICAN CYANAMID COMPANY (US) 1981-01-06 US disclosed
EP-0003663-A2 Amino-substituted phenyl and heteroaryl compounds, process for their preparation and pharmaceutical compositions containing them AMERICAN CYANAMID COMPANY (US) 1979-08-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357767-A1 NOVEL NUCLEIC ACID MOLECULE INHIBITING EXPRESSION OF TARGET GENE SNRPE, DDX21, DCLRE1B ALDH1A1 3438/4885ALOX15 4629/4885SMN1; SMN2 2121/4885
US-20230183283-A1 NOVEL GLYCOSIDE COMPOUND AND PRODUCTION METHOD THEREFOR SLC5A11, POLRMT, MAPK11 ALDH1A1 3258/4885ALOX15 2485/4885SMN1; SMN2 2393/4885
US-10377788-B2 Method for producing glycoside compounds TST, DIMT1, DERA ALDH1A1 808/4885ALOX15 2636/4885SMN1; SMN2 3768/4885
US-20180079768-A1 METHOD FOR PRODUCING GLYCOSIDE COMPOUNDS TST, DIMT1, DERA ALDH1A1 808/4885ALOX15 2636/4885SMN1; SMN2 3768/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.