Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 4/20 | 0.36 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL745473 | 0.90 | KMT2A (0.44) | ESRRGSLC13A5KMT2AMAPTNR1H4 | |
| SCHEMBL745468 | 0.90 | F2 (0.38) | CNR2SLC13A5KMT2ATP53LMNA | |
| SCHEMBL748461 | 0.89 | ESRRG (0.46) | ESRRGSLC13A5KMT2ATP53LMNA | |
| SCHEMBL747114 | 0.89 | C5AR1 (0.41) | ESRRGSLC13A5KMT2ALMNA | |
| SCHEMBL746610 | 0.89 | TP53 (0.42) | ESRRGSLC13A5KMT2ATP53LMNA | |
| SCHEMBL747130 | 0.89 | SLC13A5 (0.37) | ESRRGSLC13A5KMT2ATP53LMNA | |
| SCHEMBL748509 | 0.87 | LPAR1 (0.43) | ESRRGSLC13A5KMT2ATP53LMNA | |
| SCHEMBL747640 | 0.86 | TP53 (0.41) | ESRRGSLC13A5TP53LMNAMAPT | |
| SCHEMBL749104 | 0.85 | SLC13A5 (0.35) | ESRRGSLC13A5KMT2ATP53MAPT | |
| SCHEMBL747162 | 0.84 | TACR1 (0.37) | SLC13A5KMT2ATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8022217-B2 | Compounds suitable as modulators of HDL | CADILA HEALTHCARE LIMITED (IN) | 2011-09-20 | — | — | US | claimed |
| EP-2049493-B1 | COMPOUNDS SUITABLE AS MODULATORS OF HDL | CADILA HEALTHCARE LTD (IN) | 2012-03-21 | — | — | EP | disclosed |
| US-8022217-B2 | Compounds suitable as modulators of HDL | CADILA HEALTHCARE LIMITED (IN) | 2011-09-20 | — | — | US | disclosed |