Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | MLNR | O43193 | 2/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.44 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NMT1 | P30419 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | BPTF | Q12830 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7494810 | 0.95 | ALOX12 (0.47) | ALOX12GAAMLNRDDB1CRBN | |
| SCHEMBL30307834 | 0.85 | GAA (0.64) | ALOX12GAAMLNRDDB1CRBN | |
| SCHEMBL7485675 | 0.85 | GAA (0.64) | ALOX12GAAMLNRDDB1CRBN | |
| SCHEMBL2829665 | 0.82 | GAA (0.53) | GAAKMT2AMEN1KDM4EHSD17B10 | |
| SCHEMBL2829135 | 0.82 | GAA (0.49) | GAAKMT2AMEN1KDM4EHSD17B10 | |
| SCHEMBL7488327 | 0.81 | GAA (0.59) | ALOX12GAAMLNRDDB1CRBN | |
| SCHEMBL2824378 | 0.79 | GAA (0.49) | GAAKMT2AMEN1KDM4EHSD17B10 | |
| SCHEMBL2346509 | 0.78 | HTR6 (0.66) | ALOX12GAAMLNRDDB1CRBN | |
| SCHEMBL4686763 | 0.76 | KMT2A (0.60) | ALOX12GAAMLNRKMT2AMEN1 | |
| SCHEMBL4514895 | 0.72 | GPR119 (0.50) | GAAMLNRKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1243268-A1 | MEDICINAL COMPOSITION | Nippon Shinyaku Co., Ltd. (JP) | 2002-09-25 | — | — | EP | disclosed |
| EP-1156045-A1 | AMIDE DERIVATIVES AND DRUG COMPOSITIONS | Nippon Shinyaku Co., Ltd. (JP) | 2001-11-21 | — | — | EP | disclosed |