Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | PTPRB | P23467 | 2/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | ACP1 | P24666 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL560683 | 1.00 | ALDH1A1 (0.49) | ALDH1A1RECQLSYKPTPRBPTPN2 | |
| SCHEMBL560838 | 0.95 | ALDH1A1 (0.51) | ALDH1A1RECQLSYKPTPRBPTPN2 | |
| SCHEMBL560930 | 0.91 | ALDH1A1 (0.47) | ALDH1A1RECQLSYKPTPRBPTPN2 | |
| SCHEMBL560931 | 0.91 | ALDH1A1 (0.47) | ALDH1A1RECQLSYKPTPRBPTPN2 | |
| SCHEMBL560508 | 0.89 | PTPN2 (0.54) | ALDH1A1RECQLSYKPTPRBPTPN2 | |
| SCHEMBL560507 | 0.89 | PTPN2 (0.54) | ALDH1A1RECQLSYKPTPRBPTPN2 | |
| SCHEMBL561264 | 0.87 | PTPRB (0.53) | ALDH1A1RECQLSYKPTPRBPTPN2 | |
| SCHEMBL560612 | 0.87 | PTPN2 (0.56) | ALDH1A1RECQLSYKPTPRBPTPN2 | |
| SCHEMBL561888 | 0.85 | HTT (0.44) | ALDH1A1RECQLPTPRBMEN1KMT2A | |
| SCHEMBL561889 | 0.85 | HTT (0.44) | ALDH1A1RECQLPTPRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9434737-B2 | Process for producing optically active succinimide derivatives and intermediates thereof | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2016-09-06 | — | — | US | disclosed |
| US-20140099681-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE SUCCINIMIDE DERIVATIVES AND INTERMEDIATES THEREOF | KYOWA HAKKO BIO CO., LTD. (JP) | 2014-04-10 | — | — | US | disclosed |
| US-8633001-B2 | Process for producing optically active succinimide derivatives and intermediates thereof | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2014-01-21 | — | — | US | disclosed |
| US-20120034660-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE SUCCINIMIDE DERIVATIVES AND INTERMEDIATES THEREOF | KYOWA HAKKO BIO CO., LTD. (JP) | 2012-02-09 | — | — | US | disclosed |
| EP-2395097-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE SUCCINIMIDE DERIVATIVE AND INTERMEDIATE THEREOF | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2011-12-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140099681-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE SUCCINIMIDE DERIVATIVES AND INTERMEDIATES THEREOF | SDHA, STS, DHPS | ALDH1A1 255/4885RECQL 3355/4885SYK 1730/4885 |
| US-20120034660-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE SUCCINIMIDE DERIVATIVES AND INTERMEDIATES THEREOF | SDHA, STS, ALDH18A1 | ALDH1A1 265/4885RECQL 3614/4885SYK 1447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.