Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 19/20 | 0.62 |
| ▸ | CTSS | P25774 | 18/20 | 0.62 |
| ▸ | CTSL | P07711 | 17/20 | 0.62 |
| ▸ | CTSK | P43235 | 5/20 | 0.62 |
| ▸ | CTSD | P07339 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6183676 | 0.91 | CTSB (0.60) | CTSBCTSSCTSLCTSKCTSD | |
| SCHEMBL6184370 | 0.85 | CTSB (0.85) | CTSBCTSSCTSLCTSK | |
| SCHEMBL6183485 | 0.77 | CTSB (1.00) | CTSBCTSSCTSLCTSK | |
| SCHEMBL6184277 | 0.77 | CTSB (0.79) | CTSBCTSSCTSLCTSK | |
| SCHEMBL6181770 | 0.75 | CTSB (0.83) | CTSBCTSSCTSLCTSK | |
| SCHEMBL6183543 | 0.75 | CTSB (1.00) | CTSBCTSSCTSLCTSK | |
| Trifluoroacetic Acid SCHEMBL6182305 | 0.74 | CTSB (0.89) | CTSBCTSSCTSLCTSK | |
| SCHEMBL1118162 | 0.71 | GPR119 (0.52) | — | |
| SCHEMBL6182905 | 0.70 | CTSK (0.61) | CTSBCTSSCTSLCTSK | |
| SCHEMBL4576707 | 0.70 | CTSB (1.00) | CTSBCTSSCTSLCTSKCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001068645-A2 | N-CYANOMETHYLCARBOXAMIDES AND THEIR USE AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-09-20 | — | — | WO | claimed |