Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 4/20 | 0.72 |
| ▸ | NPY1R | P25929 | 1/20 | 0.57 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7486156 | 1.00 | CCKBR (0.72) | CCKBRNPY1RSCN9A | |
| SCHEMBL7564700 | 0.92 | CCKBR (0.63) | CCKBRSCN9A | |
| SCHEMBL7598390 | 0.92 | CCKBR (0.63) | CCKBRSCN9A | |
| SCHEMBL8673708 | 0.92 | ACE (0.66) | CCKBRNPY1RSCN9A | |
| SCHEMBL11050154 | 0.92 | ACE (0.66) | CCKBRNPY1RSCN9A | |
| SCHEMBL11182642 | 0.89 | CCKBR (0.59) | CCKBRSCN9A | |
| SCHEMBL7084907 | 0.87 | CCKBR (0.63) | CCKBRNPY1R | |
| SCHEMBL4797202 | 0.85 | PYGL (0.55) | CCKBR | |
| SCHEMBL4797181 | 0.85 | PYGL (0.55) | CCKBR | |
| SCHEMBL9600943 | 0.84 | CCKBR (1.00) | CCKBRNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4575503-A | ANGIOTENSIN CONVERTING ENZYME INHIBITOR, HYPOTENSIVE | CIBA-GEIGY CORPORATION (US) | 1986-03-11 | — | — | US | disclosed |
| US-4473575-A | ANGIOTENSIN INHIBITORS, HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1984-09-25 | — | — | US | disclosed |
| US-4410520-A | ANGIOTENSION CONVERTING ENZYME INGIBITOR, HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1983-10-18 | — | — | US | disclosed |
| EP-0072352-A1 | Benzazepin-2-ones, process for their preparation, pharmaceutical preparations containing these compounds and the compounds for therapeutical use | CIBA-GEIGY AG (CH) | 1983-02-16 | — | — | EP | disclosed |