Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 3/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7484482 | 0.81 | TDO2 (0.59) | STING1TOP2AIDO1TDO2 | |
| SCHEMBL30934638 | 0.78 | SNCA (0.48) | KIF11CYP1A2HPGDSTING1CYP2C9 | |
| SCHEMBL25025855 | 0.78 | STING1 (0.48) | KIF11CYP1A2STING1CYP2C9CYP2C19 | |
| SCHEMBL25024569 | 0.78 | STING1 (0.48) | KIF11CYP1A2ALDH1A1MEN1HPGD | |
| SCHEMBL30233809 | 0.78 | STING1 (0.48) | KIF11CYP1A2ALDH1A1MEN1HPGD | |
| SCHEMBL25025764 | 0.78 | SNCA (0.48) | KIF11CYP1A2HPGDSTING1CYP2C9 | |
| SCHEMBL31757548 | 0.78 | STING1 (0.48) | KIF11CYP1A2STING1CYP2C9CYP2C19 | |
| SCHEMBL7539607 | 0.78 | DYRK1A (0.55) | ALDH1A1STING1RXFP1GSK3BTDO2 | |
| SCHEMBL25025556 | 0.76 | STING1 (0.46) | KIF11CYP1A2STING1CYP2C9CYP2C19 | |
| SCHEMBL29226635 | 0.76 | STING1 (0.41) | KIF11CYP1A2STING1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242420-A2 | AGENTS AND METHODS FOR THE TREATMENT OF PROLIFERATIVE DISEASES | ELI LILLY AND COMPANY (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001044247-A2 | AGENTS AND METHODS FOR THE TREATMENT OF PROLIFERATIVE DISEASES | ELI LILLY AND COMPANY (US) | 2001-06-21 | — | — | WO | disclosed |