Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 10/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SORD | Q00796 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11981508 | 0.89 | MEN1 (0.62) | HTR1AMEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL7489291 | 0.82 | SORD (0.49) | HTR1ASORDKCNH2 | |
| SCHEMBL13033015 | 0.82 | SORD (0.54) | HTR1AMEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL807735 | 0.79 | MEN1 (0.54) | HTR1AMEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL9689521 | 0.79 | MEN1 (0.72) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9133699 | 0.78 | CASP1 (0.58) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9690413 | 0.78 | CASP1 (0.58) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9689535 | 0.78 | CASP1 (0.58) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9128566 | 0.78 | CASP1 (0.58) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9689152 | 0.78 | CASP1 (0.58) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023287-B1 | 3-OXO-2(H)-1,2,4-TRIAZINE DERIVATIVES AS LIGANDS OF 5HT1A RECEPTORS | PF MEDICAMENT (FR) | 2002-06-12 | — | — | EP | disclosed |
| US-6303603-B1 | FOR THEARPY OF ANXIETY, DEPRESSION, SCHIZOPHRENIA | PIERRE FABRE MEDICAMENT (FR) | 2001-10-16 | — | — | US | disclosed |