Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7486938 | 0.84 | LMNA (0.35) | POLBALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL7487029 | 0.83 | F7 (0.41) | ALDH1A1GAAMAPT | |
| Hydrochloric Acid SCHEMBL6365198 | 0.82 | F7 (0.41) | ALDH1A1GAAMAPT | |
| Hydrochloric Acid SCHEMBL7430227 | 0.81 | NAMPT (0.40) | POLBALDH1A1GAAMAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7432391 | 0.80 | HTT (0.45) | POLBALDH1A1GAAMAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7482356 | 0.76 | MTNR1A (0.40) | ALDH1A1KDM4ETSHRCYP3A4LMNA | |
| Hydrochloric Acid SCHEMBL7431195 | 0.76 | SMN1; SMN2 (0.43) | POLBALDH1A1GAAMAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6373666 | 0.74 | RECQL (0.42) | ALDH1A1GAAMAPTSMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL7425653 | 0.74 | LMNA (0.42) | ALDH1A1GAASMN1; SMN2HTTTSHR | |
| Hydrochloric Acid SCHEMBL7430474 | 0.73 | L3MBTL1 (0.44) | ALDH1A1GAAMAPTSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206444-A1 | COMPOUNDS THAT INHIBIT TRYPTASE ACTIVITY | Morphochem AG (DE) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001014320-A1 | COMPOUNDS THAT INHIBIT TRYPTASE ACTIVITY | MORPHOCHEM AG (DE) | 2001-03-01 | — | — | WO | disclosed |