Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 10/20 | 0.46 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.44 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.43 |
| ▸ | CASP2 | P42575 | 1/20 | 0.42 |
| ▸ | RRM1 | P23921 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25009804 | 0.82 | EPHX1 (0.37) | EPHX1 | |
| SCHEMBL12061986 | 0.81 | EPHX1 (0.50) | EPHX1ZDHHC20ZDHHC2DPP7CASP2 | |
| SCHEMBL25971770 | 0.79 | EPHX1 (0.54) | EPHX1ZDHHC20ZDHHC2CASP2ALDH1A1 | |
| SCHEMBL26750525 | 0.79 | EPHX1 (0.54) | EPHX1ZDHHC20ZDHHC2CASP2ALDH1A1 | |
| SCHEMBL26192818 | 0.79 | EPHX1 (0.54) | EPHX1ZDHHC20ZDHHC2CASP2ALDH1A1 | |
| SCHEMBL24133452 | 0.79 | EPHX1 (0.54) | EPHX1ZDHHC20ZDHHC2CASP2ALDH1A1 | |
| SCHEMBL8986277 | 0.79 | CASP2 (0.48) | EPHX1ZDHHC20ZDHHC2DPP7CASP2 | |
| SCHEMBL23394747 | 0.79 | CASP2 (0.48) | EPHX1ZDHHC20ZDHHC2CASP2ALDH1A1 | |
| SCHEMBL21251603 | 0.79 | CASP2 (0.54) | EPHX1ZDHHC20ZDHHC2DPP7CASP2 | |
| SCHEMBL20863007 | 0.78 | SLC6A5 (0.54) | EPHX1CASP2ALDH1A1TSHRGNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200024-B1 | 3-CYANO-PYRIDINES, PROCESS FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL USE | ARZNEIMITTELWERK DRESDEN GmbH (DE) | 1992-07-01 | — | — | EP | claimed |