SCHEMBL748718

SCHEMBL748718

CCCC1CCOC(c2ccccc2)(C(O)c2ccccc2)O1

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
GLA P06280 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HTR1A P08908 1/20 0.34
ADRA1D P25100 1/20 0.34
ADRA1A P35348 1/20 0.34
ADRA1B P35368 1/20 0.34
CHRM2 P08172 1/20 0.34
CHRM4 P08173 1/20 0.34
CHRM1 P11229 1/20 0.34
CHRM3 P20309 1/20 0.34
SIGMAR1 Q99720 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL749631 0.93 NAAA (0.34)
SCHEMBL749622 0.92 NAAA (0.36)
SCHEMBL749062 0.91 NAAA (0.38)
SCHEMBL747694 0.90 ALDH1A1 (0.36) ALDH1A1GLASMN1; SMN2HTR1AADRA1D
SCHEMBL747107 0.89 HTR1A (0.35) HTR1AADRA1DADRA1AADRA1B
SCHEMBL749051 0.87 HTR1A (0.36) HTR1AADRA1DADRA1AADRA1BCHRM2
Methyl Alcohol SCHEMBL748791 0.87 HTR1A (0.33) ALDH1A1GLASMN1; SMN2HTR1AADRA1D
SCHEMBL750090 0.86 HTR1A (0.34) ALDH1A1GLASMN1; SMN2HTR1AADRA1D
SCHEMBL747652 0.86 ALDH1A1 (0.32) ALDH1A1GLASMN1; SMN2HTR1AADRA1D
SCHEMBL751244 0.86 ALDH1A1 (0.33) ALDH1A1GLASMN1; SMN2HTR1AADRA1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2452984-A1 Degassing Compositions for Curable Coatings Troy Technology Corporation, Inc. (US) 2012-05-16 EP claimed
EP-2152812-B1 DEGASSING COMPOSITIONS FOR CURABLE COATINGS TROY TECHNOLOGY CORP INC (US) 2012-03-21 EP claimed
US-7842745-B2 Degassing compositions for curable coatings TROY CORPORATION (US) 2010-11-30 US claimed
US-20100204373-A1 Degassing compositions for curable coatings TROY CORPORATION 2010-08-12 US claimed
EP-2152812-A1 DEGASSING COMPOSITIONS FOR CURABLE COATINGS Troy Technology Corporation, Inc. (US) 2010-02-17 EP claimed
US-20090023847-A1 Degassing compositions for curable coatings TROY CORPORATION 2009-01-22 US claimed
WO-2008130538-A1 DEGASSING COMPOSITIONS FOR CURABLE COATINGS TROY TECHNOLOGY CORPORATION, INC. (US) 2008-10-30 WO claimed
EP-2452984-A1 Degassing Compositions for Curable Coatings Troy Technology Corporation, Inc. (US) 2012-05-16 EP disclosed