Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.40 |
| ▸ | F7 | P08709 | 9/20 | 0.40 |
| ▸ | F2 | P00734 | 6/20 | 0.40 |
| ▸ | MC4R | P32245 | 2/20 | 0.37 |
| ▸ | MC5R | P33032 | 2/20 | 0.37 |
| ▸ | MC3R | P41968 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | BIRC3 | Q13489 | 1/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL745473 | 0.90 | KMT2A (0.44) | KMT2ASIGMAR1SLC13A5MEN1 | |
| SCHEMBL748780 | 0.88 | TP53 (0.35) | F10F7F2KMT2ASLC13A5 | |
| SCHEMBL748523 | 0.88 | LPAR1 (0.38) | KMT2ASIGMAR1SLC13A5 | |
| SCHEMBL745501 | 0.88 | TMEM97 (0.39) | KMT2ASIGMAR1SLC13A5 | |
| SCHEMBL748461 | 0.88 | ESRRG (0.46) | KMT2ASLC13A5MEN1 | |
| Hydrochloric Acid SCHEMBL752637 | 0.87 | TMEM97 (0.38) | KMT2ASIGMAR1SLC13A5 | |
| SCHEMBL749530 | 0.87 | NR1I2 (0.45) | F10F7F2KMT2ASIGMAR1 | |
| SCHEMBL748509 | 0.87 | LPAR1 (0.43) | KMT2ASLC13A5MEN1 | |
| SCHEMBL747114 | 0.87 | C5AR1 (0.41) | KMT2ASLC13A5MEN1 | |
| SCHEMBL747130 | 0.87 | SLC13A5 (0.37) | KMT2ASLC13A5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049493-B1 | COMPOUNDS SUITABLE AS MODULATORS OF HDL | CADILA HEALTHCARE LTD (IN) | 2012-03-21 | — | — | EP | claimed |
| US-8022217-B2 | Compounds suitable as modulators of HDL | CADILA HEALTHCARE LIMITED (IN) | 2011-09-20 | — | — | US | claimed |
| EP-2049493-B1 | COMPOUNDS SUITABLE AS MODULATORS OF HDL | CADILA HEALTHCARE LTD (IN) | 2012-03-21 | — | — | EP | disclosed |
| US-8022217-B2 | Compounds suitable as modulators of HDL | CADILA HEALTHCARE LIMITED (IN) | 2011-09-20 | — | — | US | disclosed |