⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7497572 | 0.76 | — | — | |
| SCHEMBL7493272 | 0.73 | — | — | |
| SCHEMBL7490703 | 0.70 | PI4KA (0.32) | — | |
| SCHEMBL838220 | 0.63 | — | — | |
| SCHEMBL7496566 | 0.61 | ADORA3 (0.32) | — | |
| SCHEMBL18493465 | 0.60 | MAPK1 (0.35) | — | |
| SCHEMBL857662 | 0.58 | LMNA (0.39) | — | |
| SCHEMBL855773 | 0.58 | NQO2 (0.41) | — | |
| SCHEMBL20142655 | 0.55 | — | — | |
| SCHEMBL22337376 | 0.55 | GAA (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915093-B1 | AMIDE DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 2002-11-27 | — | — | EP | disclosed |
| US-6166016-A | Amide derivatives | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-12-26 | — | — | US | disclosed |
| EP-0915093-A1 | AMIDE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1999-05-12 | — | — | EP | disclosed |