Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27181728 | 0.77 | IDO1 (0.33) | — | |
| SCHEMBL1639797 | 0.73 | CRHBP (0.33) | KMT2A | |
| SCHEMBL14830999 | 0.73 | NCF1 (0.37) | KMT2AKDM4E | |
| SCHEMBL21672130 | 0.72 | — | — | |
| SCHEMBL7509409 | 0.72 | CCR1 (0.58) | GAAKMT2ACCR1RAB9ACCR5 | |
| SCHEMBL22338015 | 0.70 | CYP1A2 (0.45) | GAAKMT2ACCR1RAB9ACCR5 | |
| SCHEMBL30620039 | 0.70 | ALDH1A1 (0.35) | KMT2ACYP1A2POLB | |
| SCHEMBL24991184 | 0.69 | NOS3 (0.33) | — | |
| SCHEMBL2022194 | 0.67 | KDM4E (0.49) | KMT2ARAB9AKDM4ELMNA | |
| SCHEMBL291014 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020163193-A1 | BICYCLIC ETHER O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS | BIOGEN MA INC. (US) | 2020-08-13 | — | — | WO | disclosed |