Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | BRD2 | P25440 | 2/20 | 0.36 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7107876 | 0.71 | HSD17B10 (0.40) | KMT2AMEN1MAPTHTTNPSR1 | |
| SCHEMBL7109054 | 0.70 | TSHR (0.38) | KMT2AMAPTHTTNPSR1TSHR | |
| SCHEMBL6982804 | 0.69 | HTT (0.51) | KMT2AMEN1HTTTSHRLMNA | |
| SCHEMBL6984551 | 0.68 | ALDH1A1 (0.45) | KMT2AMEN1MAPTHTTTSHR | |
| SCHEMBL12439899 | 0.65 | PKM (0.45) | KMT2AMEN1MAPTHTTTSHR | |
| SCHEMBL7573640 | 0.64 | ALDH1A1 (0.57) | KMT2AMEN1MAPTHTTTSHR | |
| SCHEMBL7573668 | 0.60 | HTT (0.47) | KMT2AMEN1MAPTHTTTSHR | |
| SCHEMBL4950654 | 0.60 | HTR1A (0.50) | KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL31666386 | 0.60 | HTR1A (0.50) | KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7103628 | 0.60 | MAPT (0.39) | KMT2AMEN1MAPTTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975630-B1 | SULFONYLOXADIAZOLONES AND THEIR USE AS MICROBICIDES | BAYER AG (DE) | 2002-09-18 | — | — | EP | disclosed |
| US-6136830-A | BACTERICIDES AND FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-10-24 | — | — | US | disclosed |
| EP-0975630-A1 | SULFONYLOXADIAZOLONES AND THEIR USE AS MICROBICIDES | BAYER AG (DE) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998047897-A1 | SULFONYLOXADIAZOLONES AND THEIR USE AS MICROBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-10-29 | — | — | WO | disclosed |