Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 15/20 | 0.47 |
| ▸ | MMP2 | P08253 | 5/20 | 0.42 |
| ▸ | MMP3 | P08254 | 4/20 | 0.42 |
| ▸ | MMP9 | P14780 | 4/20 | 0.42 |
| ▸ | MMP7 | P09237 | 3/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | FCER2 | P06734 | 6/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 3/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7481783 | 0.86 | MMP1 (0.48) | MMP1MMP2MMP3MMP9MMP7 | |
| SCHEMBL7429302 | 0.84 | MMP1 (0.55) | MMP1MMP2MMP9MMP8REN | |
| SCHEMBL7420777 | 0.84 | MMP1 (0.41) | MMP1MMP2MMP3MMP9MMP7 | |
| SCHEMBL7482029 | 0.84 | MMP1 (0.41) | MMP1MMP2MMP3MMP9MMP8 | |
| SCHEMBL7426256 | 0.83 | MMP1 (0.54) | MMP1MMP2MMP3MMP9MMP7 | |
| SCHEMBL6416218 | 0.81 | MMP1 (0.56) | MMP1MMP2MMP3MMP9MMP7 | |
| SCHEMBL7424750 | 0.81 | MMP1 (0.46) | MMP1MMP2MMP3CAPN1REN | |
| SCHEMBL7427886 | 0.77 | MMP1 (0.47) | MMP1CAPN1REN | |
| SCHEMBL7887188 | 0.77 | MMP1 (0.54) | MMP1MMP2MMP3MMP9MMP7 | |
| SCHEMBL6412175 | 0.77 | MMP1 (0.54) | MMP1MMP2MMP3MMP9MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047450-A1 | ACE INHIBITOR-MMP INHIBITOR COMBINATIONS | WARNER-LAMBERT COMPANY (US) | 2000-11-02 | — | — | EP | disclosed |
| WO-1999032150-A1 | ACE INHIBITOR-MMP INHIBITOR COMBINATIONS | WARNER-LAMBERT COMPANY (US) | 1999-07-01 | — | — | WO | disclosed |