Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | STAT1 | P42224 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7490046 | 0.88 | ALDH1A1 (0.35) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL7488126 | 0.87 | PRKCI (0.42) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL7494921 | 0.83 | SLC10A2 (0.44) | ALDH1A1MAPTGAAKDM4EABCG2 | |
| SCHEMBL7490926 | 0.82 | CYP2C9 (0.42) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL7490054 | 0.75 | PRKCI (0.45) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL7683887 | 0.72 | SLC10A2 (0.42) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL7493393 | 0.71 | SLC10A2 (0.47) | ALDH1A1MAPTGAAKDM4EABCG2 | |
| SCHEMBL7820217 | 0.71 | SLC10A2 (0.41) | ALDH1A1MAPTPOLBHPGDGAA | |
| SCHEMBL7494845 | 0.71 | PRKCI (0.48) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL7495269 | 0.71 | PRKCI (0.46) | ALDH1A1MAPTMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791000-B1 | THIENOPYRIDINE OR THIENOPYRIMIDINE DERIVATIVES AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-10-02 | — | — | EP | disclosed |
| EP-0791000-A1 | THIENOPYRIDINE OR THIENOPYRIMIDINE DERIVATIVES AND THEIR USE | Takeda Chemical Industries, Ltd. (JP) | 1997-08-27 | — | — | EP | disclosed |
| WO-1996014319-A1 | THIENOPYRIDINE OR THIENOPYRIMIDINE DERIVATIVES AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-17 | — | — | WO | disclosed |