Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7494845 | 0.89 | PRKCI (0.48) | PRKCIPRKCZHSD17B10KDM4ETP53 | |
| SCHEMBL7490054 | 0.87 | PRKCI (0.45) | PRKCIPRKCZHSD17B10KDM4ETP53 | |
| SCHEMBL7488126 | 0.84 | PRKCI (0.42) | PRKCIPRKCZHSD17B10KDM4ETP53 | |
| SCHEMBL7485921 | 0.83 | SLC10A2 (0.48) | KDM4ESMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7494813 | 0.83 | MAPT (0.44) | PRKCZKDM4ETP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL7485972 | 0.82 | MAPT (0.53) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7484725 | 0.74 | ABCC1 (0.40) | HSD17B10KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL7490046 | 0.73 | ALDH1A1 (0.35) | HSD17B10KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL3384951 | 0.73 | PRKCZ (0.66) | PRKCIPRKCZHSD17B10KDM4ETP53 | |
| SCHEMBL7495290 | 0.73 | CYP2C9 (0.41) | PRKCZKDM4ETP53SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791000-B1 | THIENOPYRIDINE OR THIENOPYRIMIDINE DERIVATIVES AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-10-02 | — | — | EP | disclosed |
| US-5747486-A | ANTIINFLAMMATORY AGENTS | TAKEDA CHEMICAL INDUSTRIES (JP) | 1998-05-05 | — | — | US | disclosed |
| EP-0791000-A1 | THIENOPYRIDINE OR THIENOPYRIMIDINE DERIVATIVES AND THEIR USE | Takeda Chemical Industries, Ltd. (JP) | 1997-08-27 | — | — | EP | disclosed |
| WO-1996014319-A1 | THIENOPYRIDINE OR THIENOPYRIMIDINE DERIVATIVES AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-17 | — | — | WO | disclosed |