Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 11/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 11/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PARP15 | Q460N3 | 10/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 8/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL7483044 | 0.98 | TNKS2 (0.35) | TNKS2PARP2MEN1CYP1A2POLB | |
| Bromide SCHEMBL7483053 | 0.73 | POLB (0.39) | TNKS2PARP2MEN1CYP1A2POLB | |
| SCHEMBL20518804 | 0.70 | ALDH1A1 (0.35) | MEN1POLBKMT2AELANEALDH1A1 | |
| SCHEMBL7479395 | 0.67 | SMN1; SMN2 (0.62) | MEN1POLBKMT2AALDH1A1KDM4E | |
| Bromide SCHEMBL7479450 | 0.66 | SMN1; SMN2 (0.64) | MEN1POLBKMT2AALDH1A1KDM4E | |
| SCHEMBL7477728 | 0.66 | KDM4E (0.40) | TNKS2PARP2POLBKMT2APARP15 | |
| SCHEMBL7487088 | 0.63 | SMN1; SMN2 (0.46) | MEN1POLBKMT2AALDH1A1MAPK1 | |
| SCHEMBL4014392 | 0.54 | TNKS2 (0.44) | TNKS2PARP2KMT2APARP15PARP10 | |
| SCHEMBL19028806 | 0.54 | PDPK1 (0.47) | HSD17B10PLK1CSNK2A1PLK3 | |
| SCHEMBL31696695 | 0.53 | PLK1 (0.44) | MEN1KMT2AELANEALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0843681-B1 | HETEROCYCLE-FUSED THIAZOLE DERIVATIVES | YUNGJIN PHARMACEUTICAL CO LTD (KR) | 2002-03-06 | — | — | EP | disclosed |