Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | PI4KA | P42356 | 1/20 | 0.37 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.37 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7492011 | 0.99 | CYP19A1 (0.40) | ADORA2BSMN1; SMN2RXFP1TLR7POLB | |
| SCHEMBL7492336 | 0.96 | PDE4A (0.39) | ADORA2BSMN1; SMN2RXFP1POLBHIF1A | |
| SCHEMBL7489441 | 0.93 | YTHDC1 (0.41) | ADORA2BSMN1; SMN2RXFP1POLBHIF1A | |
| SCHEMBL7488831 | 0.86 | ADORA2A (0.44) | ADORA2BSMN1; SMN2RXFP1YTHDC1ADORA2A | |
| SCHEMBL7491743 | 0.86 | TSHR (0.41) | ADORA2BPOLBADORA2A | |
| SCHEMBL7488843 | 0.86 | CNOT7 (0.43) | ADORA2BADORA2A | |
| SCHEMBL7486698 | 0.85 | TSHR (0.41) | ADORA2BPOLBADORA2A | |
| SCHEMBL7488311 | 0.85 | TSHR (0.41) | ADORA2BPOLBADORA2A | |
| SCHEMBL7492592 | 0.85 | TSHR (0.45) | ADORA2BTLR7POLBADORA2A | |
| SCHEMBL7494220 | 0.81 | GPR84 (0.39) | ADORA2BSMN1; SMN2RXFP1TLR7POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915093-B1 | AMIDE DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 2002-11-27 | — | — | EP | disclosed |
| US-6166016-A | Amide derivatives | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-12-26 | — | — | US | disclosed |
| EP-0915093-A1 | AMIDE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1999-05-12 | — | — | EP | disclosed |