Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | PNP | P00491 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7492336 | 0.94 | PDE4A (0.39) | YTHDC1ADORA2BSMN1; SMN2RXFP1ADORA2A | |
| SCHEMBL7488243 | 0.93 | ADORA2B (0.40) | YTHDC1ADORA2BSMN1; SMN2RXFP1ADORA2A | |
| SCHEMBL7492011 | 0.92 | CYP19A1 (0.40) | YTHDC1ADORA2BSMN1; SMN2RXFP1POLB | |
| SCHEMBL7488831 | 0.91 | ADORA2A (0.44) | YTHDC1ADORA2BSMN1; SMN2RXFP1ADORA2A | |
| SCHEMBL7488843 | 0.83 | CNOT7 (0.43) | ADORA2BADORA2AHTTPDE4APDE4B | |
| SCHEMBL7484132 | 0.82 | YTHDC1 (0.44) | YTHDC1ADORA2BSMN1; SMN2RXFP1ADORA2A | |
| SCHEMBL7492592 | 0.82 | TSHR (0.45) | ADORA2BADORA2APOLB | |
| SCHEMBL7491743 | 0.81 | TSHR (0.41) | ADORA2BADORA2APOLB | |
| SCHEMBL7488311 | 0.80 | TSHR (0.41) | ADORA2BADORA2APOLB | |
| SCHEMBL7486698 | 0.80 | TSHR (0.41) | ADORA2BADORA2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915093-B1 | AMIDE DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 2002-11-27 | — | — | EP | disclosed |
| US-6166016-A | Amide derivatives | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-12-26 | — | — | US | disclosed |
| EP-0915093-A1 | AMIDE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1999-05-12 | — | — | EP | disclosed |