Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 6/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.36 |
| ▸ | PDE2A | O00408 | 2/20 | 0.36 |
| ▸ | PPOX | P50336 | 1/20 | 0.33 |
| ▸ | USP8 | P40818 | 1/20 | 0.32 |
| ▸ | USP7 | Q93009 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CCR6 | P51684 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7690601 | 0.89 | HSP90AB1 (0.39) | HSP90AB1HSP90AA1SRCPDE10APDE2A | |
| SCHEMBL7819187 | 0.83 | PPOX (0.36) | PPOX | |
| SCHEMBL7811968 | 0.83 | NPC1 (0.31) | RAB9A | |
| SCHEMBL7818695 | 0.82 | SLC34A1 (0.30) | RAB9A | |
| SCHEMBL7811612 | 0.82 | AR (0.34) | PDE10A | |
| SCHEMBL5398257 | 0.80 | CYP1A2 (0.35) | HSP90AB1HSP90AA1PDE10APDE2APPOX | |
| SCHEMBL7686734 | 0.77 | HSP90AB1 (0.49) | HSP90AB1HSP90AA1SRCPDE10APDE2A | |
| SCHEMBL6295368 | 0.77 | PDE10A (0.33) | HSP90AB1HSP90AA1SRCPDE10APDE2A | |
| SCHEMBL9530563 | 0.77 | PTGS2 (0.39) | PDE10APDE2APPOXEIF2AK3ALDH1A1 | |
| SCHEMBL7487729 | 0.76 | MAPT (0.41) | PPOXALDH1A1MAPTRAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0769008-B1 | PYRAZOLE DERIVATIVES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2002-05-22 | — | — | EP | disclosed |
| US-6083881-A | Pyrazole derivatives as herbicides | NOVARTIS CORPORATION (US) | 2000-07-04 | — | — | US | disclosed |
| EP-0769008-A1 | PYRAZOLE DERIVATIVES AS HERBICIDES | Novartis AG (CH) | 1997-04-23 | — | — | EP | disclosed |
| WO-1996001254-A1 | PYRAZOLE DERIVATIVES AS HERBICIDES | CIBA-GEIGY AG (CH) | 1996-01-18 | — | — | WO | disclosed |