Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 7/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 7/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 3/20 | 0.34 |
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | BCR | P11274 | 1/20 | 0.33 |
| ▸ | USP8 | P40818 | 1/20 | 0.33 |
| ▸ | USP7 | Q93009 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7690601 | 0.89 | HSP90AB1 (0.39) | HSP90AB1HSP90AA1KCNH2SRCPDE2A | |
| SCHEMBL7694982 | 0.83 | PGK1 (0.40) | HSP90AB1HSP90AA1KCNH2 | |
| SCHEMBL7689395 | 0.81 | HSP90AA1 (0.31) | HSP90AB1HSP90AA1 | |
| SCHEMBL7694251 | 0.81 | HSP90AA1 (0.31) | HSP90AB1HSP90AA1 | |
| SCHEMBL7693284 | 0.81 | AR (0.33) | HSP90AB1HSP90AA1 | |
| SCHEMBL7489274 | 0.77 | HSP90AB1 (0.38) | HSP90AB1HSP90AA1KCNH2SRCPDE2A | |
| SCHEMBL7692799 | 0.73 | PGK1 (0.38) | — | |
| SCHEMBL7688339 | 0.70 | LMNA (0.32) | PDE10A | |
| SCHEMBL7686737 | 0.70 | PDE10A (0.30) | PDE10A | |
| SCHEMBL7687809 | 0.70 | AR (0.33) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6339046-B1 | FOR CONTROLLING WEEDS | SYNGENTA INVESTMENT CORPORATION | 2002-01-15 | — | — | US | disclosed |
| EP-0839808-A1 | Pyrazole derivatives, processes for their preparation, and their use as herbicides | Novartis AG (CH) | 1998-05-06 | — | — | EP | disclosed |