Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | EED | O75530 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL7484876 | 0.99 | CYP17A1 (0.34) | MEN1KMT2ADRD4DRD3CYP17A1 | |
| SCHEMBL7481508 | 0.82 | MEN1 (0.36) | MEN1KMT2ADRD4DRD3CYP17A1 | |
| Hydrochloric Acid SCHEMBL7482682 | 0.81 | MEN1 (0.36) | MEN1KMT2ADRD4DRD3CYP17A1 | |
| SCHEMBL7478486 | 0.81 | KMT2A (0.47) | MEN1KMT2ADRD4DRD3CYP3A4 | |
| SCHEMBL7476993 | 0.81 | DRD3 (0.52) | MEN1KMT2ADRD4DRD3DRD2 | |
| Hydrochloric Acid SCHEMBL7474283 | 0.80 | DRD3 (0.51) | MEN1KMT2ADRD4DRD3DRD2 | |
| SCHEMBL7480264 | 0.80 | DRD1 (0.43) | DRD4DRD3CYP11B2DRD2DRD1 | |
| SCHEMBL7484532 | 0.77 | KMT2A (0.42) | MEN1KMT2ADRD4DRD3 | |
| SCHEMBL7484538 | 0.77 | KMT2A (0.39) | MEN1KMT2ADRD4DRD3 | |
| SCHEMBL7478986 | 0.75 | CYP1A2 (0.30) | MEN1KMT2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0950056-B1 | N-(PYRIDINYLAMINO)ISOINDOLINES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2002-09-18 | — | — | EP | claimed |
| CN-1242012-A | N- (pyridylamino) isoindolines and related compounds | HOECHST MARION ROUSSEL INC (US) | 2000-01-19 | — | — | CN | claimed |
| EP-0950056-A2 | N-(PYRIDINYLAMINO)ISOINDOLINES AND RELATED COMPOUNDS | HOECHST MARION ROUSSEL, INC. (US) | 1999-10-20 | — | — | EP | claimed |
| WO-1998029407-A2 | N-(PYRIDINYLAMINO)ISOINDOLINES FOR TREATING ALZHEIMER'S AND DEPRESSION | HOECHST MARION ROUSSEL, INC. (US) | 1998-07-09 | — | — | WO | claimed |