Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.35 |
| ▸ | CCR9 | P51686 | 1/20 | 0.35 |
| ▸ | CTSC | P53634 | 1/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7443187 | 1.00 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3ACSS2HRH3 | |
| SCHEMBL10022331 | 0.78 | ACSS2 (0.44) | ACSS2HRH3CCR9CYP11B1CYP11B2 | |
| SCHEMBL7489848 | 0.73 | SLC6A4 (0.48) | SLC6A2SLC6A4SLC6A3ACSS2HRH3 | |
| SCHEMBL7490721 | 0.73 | SLC6A4 (0.48) | SLC6A2SLC6A4SLC6A3ACSS2HRH3 | |
| SCHEMBL7491564 | 0.70 | SLC6A4 (0.49) | SLC6A2SLC6A4SLC6A3HRH3DRD2 | |
| SCHEMBL7452507 | 0.70 | SLC6A4 (0.49) | SLC6A2SLC6A4SLC6A3HRH3DRD2 | |
| SCHEMBL7953013 | 0.70 | CHRM3 (0.39) | HRH3CHRM3 | |
| SCHEMBL7491888 | 0.69 | SLC6A4 (0.38) | SLC6A2SLC6A4SLC6A3ACSS2HRH3 | |
| SCHEMBL7491878 | 0.69 | SLC6A4 (0.38) | SLC6A2SLC6A4SLC6A3ACSS2HRH3 | |
| SCHEMBL7491601 | 0.68 | CYP11B2 (0.46) | ACSS2CCR9CYP11B1CYP11B2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918768-B1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RES LAB (KR) | 2002-01-09 | — | — | EP | disclosed |
| US-6201006-B1 | ANTICOAGULANTS | C & C RESEARCH LABORATORIES (KR) | 2001-03-13 | — | — | US | disclosed |
| EP-0918768-A1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C Research Laboratories (KR) | 1999-06-02 | — | — | EP | disclosed |
| WO-1997045424-A1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RESEARCH LABORATORIES (KR) | 1997-12-04 | — | — | WO | disclosed |