Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7492499 | 0.84 | EDNRA (0.59) | EDNRAEDNRB | |
| SCHEMBL7472885 | 0.80 | CCR2 (0.48) | EDNRAEDNRB | |
| SCHEMBL8590639 | 0.80 | EDNRA (0.64) | EDNRAEDNRB | |
| SCHEMBL8856638 | 0.78 | EDNRA (0.78) | EDNRAEDNRB | |
| SCHEMBL8540948 | 0.78 | EDNRA (0.72) | EDNRAEDNRB | |
| SCHEMBL8592047 | 0.78 | EDNRB (0.59) | EDNRAEDNRB | |
| SCHEMBL8543571 | 0.78 | EDNRB (0.69) | EDNRAEDNRB | |
| SCHEMBL8856822 | 0.77 | EDNRA (0.70) | EDNRAEDNRB | |
| SCHEMBL8856815 | 0.76 | EDNRB (0.74) | EDNRAEDNRB | |
| SCHEMBL8856658 | 0.76 | EDNRB (0.63) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242075-A4 | INDOLE COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2002-12-04 | — | — | EP | disclosed |
| EP-1242075-A2 | INDOLE COMPOUNDS | SmithKline Beecham Corporation (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001030752-A2 | INDOLE COMPOUNDS FOR TREATING BACTERIAL INFECTIONS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-03 | — | — | WO | disclosed |