Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ELANE | P08246 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.42 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.42 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.42 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.42 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7487247 | 0.83 | ATM (0.50) | L3MBTL1ELANEALDH1A1HPGDATM | |
| SCHEMBL27486176 | 0.83 | ELANE (0.43) | L3MBTL1ELANEALDH1A1HPGDATM | |
| SCHEMBL7489481 | 0.81 | ATM (0.47) | L3MBTL1ELANEALDH1A1HPGDATM | |
| SCHEMBL13760153 | 0.80 | PTGS1 (0.54) | L3MBTL1ELANEALDH1A1HPGDATM | |
| SCHEMBL30545023 | 0.77 | NPC1 (0.48) | ALDH1A1RAB9ANPC1LMNAHTT | |
| SCHEMBL11550242 | 0.76 | MAPK8 (0.54) | ALDH1A1HPGDRAB9ANPC1POLB | |
| Hydrochloric Acid SCHEMBL28247981 | 0.75 | MAPK8 (0.52) | ALDH1A1HPGDRAB9ANPC1POLB | |
| SCHEMBL10007010 | 0.72 | SMN1; SMN2 (0.71) | L3MBTL1ELANEALDH1A1HPGDATM | |
| SCHEMBL166495 | 0.72 | SMN1; SMN2 (0.71) | L3MBTL1ELANEALDH1A1HPGDATM | |
| SCHEMBL2270464 | 0.72 | MAPT (0.63) | L3MBTL1ALDH1A1HPGDATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1201661-A1 | HETEROAROMATIC RING COMPOUNDS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2002-05-02 | — | — | EP | disclosed |