Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 6/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7490444 | 0.83 | L3MBTL1 (0.43) | ELANEL3MBTL1ATMTDP1PBRM1 | |
| SCHEMBL27485833 | 0.82 | ATM (0.46) | ELANEL3MBTL1ATMTDP1PBRM1 | |
| Hydrochloric Acid SCHEMBL10735562 | 0.74 | ATM (0.50) | ELANEL3MBTL1ATMTDP1PBRM1 | |
| SCHEMBL28767763 | 0.72 | NPC1 (0.54) | L3MBTL1ATMTDP1RAB9A | |
| SCHEMBL4797796 | 0.70 | RAB9A (0.62) | L3MBTL1ATMTDP1ALDH1A1HPGD | |
| SCHEMBL11790828 | 0.70 | ALDH1A1 (0.52) | L3MBTL1PBRM1ALDH1A1HPGDRAB9A | |
| SCHEMBL26998263 | 0.70 | ATM (0.57) | ELANEL3MBTL1ATMTDP1PBRM1 | |
| SCHEMBL5074190 | 0.70 | L3MBTL1 (0.57) | ELANEL3MBTL1ATMTDP1PBRM1 | |
| SCHEMBL27486177 | 0.70 | CFD (0.42) | ALDH1A1 | |
| SCHEMBL7104771 | 0.68 | ATM (0.55) | ELANEL3MBTL1ATMTDP1PBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1202095-C | Heteroaromatic ring compounds | SUMITOMO PHARMA (JP) | 2005-05-18 | — | — | CN | disclosed |
| CN-1361770-A | Heteroaromatic ring compounds | SUMITOMO PHARMA (JP) | 2002-07-31 | — | — | CN | disclosed |