Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.50 |
| ▸ | SCN7A | Q01118 | 4/20 | 0.50 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.47 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | USP14 | P54578 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27401589 | 0.82 | PPARG (0.43) | HRH3 | |
| SCHEMBL16168681 | 0.79 | CYP2A6 (0.47) | SCN7AKCNH2 | |
| SCHEMBL7490906 | 0.78 | SLC6A4 (0.52) | HRH3KCNH2 | |
| SCHEMBL7491878 | 0.77 | SLC6A4 (0.38) | HRH3KCNH2 | |
| SCHEMBL7491888 | 0.77 | SLC6A4 (0.38) | HRH3KCNH2 | |
| SCHEMBL7489848 | 0.77 | SLC6A4 (0.48) | HRH3SCN7A | |
| SCHEMBL7490721 | 0.77 | SLC6A4 (0.48) | HRH3SCN7A | |
| SCHEMBL7435149 | 0.76 | ACSS2 (0.44) | SCN7AKCNH2 | |
| SCHEMBL7220183 | 0.76 | CYP11B2 (0.43) | SCN7AKCNH2 | |
| SCHEMBL7495800 | 0.76 | ACSS2 (0.41) | HRH3SCN7AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918768-B1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RES LAB (KR) | 2002-01-09 | — | — | EP | disclosed |
| US-6201006-B1 | ANTICOAGULANTS | C & C RESEARCH LABORATORIES (KR) | 2001-03-13 | — | — | US | disclosed |