Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AANAT | Q16613 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HAT1 | O14929 | 1/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7490766 | 0.86 | GSK3B (0.46) | AANATALDH1A1HAT1EP300MEN1 | |
| Hydrochloric Acid SCHEMBL6366448 | 0.85 | GSK3B (0.45) | AANATALDH1A1HAT1EP300MEN1 | |
| Hydrochloric Acid SCHEMBL7429245 | 0.85 | MEN1 (0.39) | ALDH1A1HAT1EP300MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7491587 | 0.84 | SIRT2 (0.49) | AANATALDH1A1MEN1KMT2ABCHE | |
| Hydrochloric Acid SCHEMBL7114154 | 0.83 | AANAT (0.48) | AANATALDH1A1MEN1KMT2ABCHE | |
| SCHEMBL7428761 | 0.77 | KMT2A (0.41) | ALDH1A1MEN1KMT2AKDM4ETSHR | |
| Hydrochloric Acid SCHEMBL7487434 | 0.77 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL7491674 | 0.76 | ACHE (0.39) | MEN1KMT2AACHEHDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL6365477 | 0.74 | MEN1 (0.44) | AANATALDH1A1MEN1KMT2AGSK3B | |
| Hydrochloric Acid SCHEMBL6366560 | 0.73 | MEN1 (0.46) | AANATMEN1KMT2AGSK3BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206444-A1 | COMPOUNDS THAT INHIBIT TRYPTASE ACTIVITY | Morphochem AG (DE) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001014320-A1 | COMPOUNDS THAT INHIBIT TRYPTASE ACTIVITY | MORPHOCHEM AG (DE) | 2001-03-01 | — | — | WO | disclosed |