Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 10/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 9/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7708858 | 0.76 | CSNK2A1 (0.49) | ADORA2AADORA1KDM4EALDH1A1HPGD | |
| SCHEMBL12242279 | 0.74 | ALDH1A1 (0.44) | ADORA2AADORA1KDM4EALDH1A1HPGD | |
| SCHEMBL13212634 | 0.72 | ADORA1 (0.49) | ADORA2AADORA1KDM4EALDH1A1HPGD | |
| SCHEMBL13359673 | 0.70 | KDM4E (0.40) | ADORA2AADORA1KDM4EALDH1A1HPGD | |
| SCHEMBL12220566 | 0.69 | GRM5 (0.43) | ADORA2AADORA1KDM4EALDH1A1HPGD | |
| SCHEMBL13316719 | 0.69 | CHEK1 (0.48) | ADORA2AADORA1KDM4EALDH1A1HPGD | |
| SCHEMBL5450251 | 0.68 | LMNA (0.47) | ADORA2AADORA1KDM4EALDH1A1HPGD | |
| SCHEMBL7703071 | 0.68 | ADORA2A (0.46) | ADORA2AADORA1KDM4EALDH1A1HPGD | |
| SCHEMBL4911494 | 0.67 | ADORA1 (1.00) | ADORA2AADORA1KDM4EALDH1A1HPGD | |
| SCHEMBL31120336 | 0.67 | ADORA1 (1.00) | ADORA2AADORA1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214322-A2 | AMINO-TRIAZOLOPYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-06-19 | — | — | EP | disclosed |
| US-6355653-B1 | DRUG AND CARRIER FOR ANTIALLERGENS, BRAIN DISORDERS AND NEUROTRANSMITTERS | HOFFMANN-LA ROCHE INC. | 2002-03-12 | — | — | US | disclosed |
| WO-2001017999-A2 | AMINO-TRIAZOLOPYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2001-03-15 | — | — | WO | disclosed |