Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ECE1 | P42892 | 2/20 | 0.32 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7491734 | 1.00 | SMN1; SMN2 (0.37) | SMN1; SMN2CA14ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL7490942 | 1.00 | SMN1; SMN2 (0.37) | SMN1; SMN2CA14ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL27454747 | 0.79 | TET2 (0.38) | SMN1; SMN2CA14KMT2A | |
| SCHEMBL1691025 | 0.78 | TSHR (0.43) | SMN1; SMN2CA14KMT2ACA1CA2 | |
| SCHEMBL9040323 | 0.78 | SMN1; SMN2 (0.52) | SMN1; SMN2KMT2ACA1CA2LMNA | |
| SCHEMBL8060426 | 0.78 | ALDH1A1 (0.42) | SMN1; SMN2CA14ALDH1A1KMT2ACA1 | |
| SCHEMBL222024 | 0.78 | SMN1; SMN2 (0.52) | SMN1; SMN2KMT2ACA1CA2LMNA | |
| SCHEMBL206973 | 0.78 | SMN1; SMN2 (0.52) | SMN1; SMN2KMT2ACA1CA2LMNA | |
| SCHEMBL1823637 | 0.78 | TSHR (0.43) | SMN1; SMN2CA14KMT2ACA1CA2 | |
| SCHEMBL205700 | 0.78 | TSHR (0.43) | SMN1; SMN2CA14KMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638075-B1 | THIAZOLE OR IMIDAZOLE DERIVATIVES AS MAILLARD REACTION INHIBITORS | OTSUKA PHARMA CO LTD (JP) | 2002-01-16 | — | — | EP | disclosed |
| US-5677322-A | THERAPY FOR AGING, DIABETES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-10-14 | — | — | US | disclosed |