Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.46 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.46 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | ALKBH1 | Q13686 | 2/20 | 0.41 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5383065 | 0.89 | MEN1 (0.44) | MEN1KMT2AP2RY14GSTP1S1PR5 | |
| SCHEMBL5382756 | 0.82 | MEN1 (0.43) | MEN1KMT2AP2RY14GSTP1TSHR | |
| SCHEMBL5393626 | 0.81 | GSTP1 (0.45) | MEN1KMT2AP2RY14GSTP1CYP4F2 | |
| SCHEMBL5377296 | 0.81 | PTGER3 (0.51) | MEN1KMT2AP2RY14GSTP1 | |
| SCHEMBL5377289 | 0.81 | PTGER3 (0.51) | MEN1KMT2AP2RY14GSTP1 | |
| SCHEMBL7539595 | 0.79 | MAOB (0.47) | MEN1KMT2AGSTP1 | |
| SCHEMBL5377062 | 0.78 | LTB4R (0.46) | MEN1KMT2AP2RY14GSTP1 | |
| SCHEMBL5385365 | 0.78 | S1PR5 (0.51) | MEN1KMT2AGSTP1S1PR5SMN1; SMN2 | |
| SCHEMBL5377058 | 0.77 | BACE1 (0.43) | MEN1KMT2AP2RY14 | |
| SCHEMBL5382479 | 0.76 | P2RY14 (0.47) | MEN1KMT2AP2RY14GSTP1S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1228067-A1 | 5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGYLCEMIC AND HYPOLIPIDEMIC ACTIVITY | Takeda Chemical Industries, Ltd. (JP) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001038325-A1 | 5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-31 | — | — | WO | disclosed |