Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | MGAM | O43451 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | SI | P14410 | 4/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7549200 | 0.89 | REV1 (0.49) | MGAMGAASIMGAM2GSTP1 | |
| SCHEMBL7541818 | 0.86 | ALOX5 (0.48) | MAOBMGAMGAASIMGAM2 | |
| SCHEMBL5382756 | 0.81 | MEN1 (0.43) | MAOBPIN1GSTP1CD274HSP90AA1 | |
| SCHEMBL5383065 | 0.80 | MEN1 (0.44) | MAOBGSTP1MEN1KMT2A | |
| SCHEMBL5393626 | 0.80 | GSTP1 (0.45) | MAOBPIN1GSTP1ERN1BCHE | |
| SCHEMBL7491027 | 0.79 | MEN1 (0.51) | GSTP1MEN1KMT2A | |
| SCHEMBL28080889 | 0.76 | GSTP1 (0.55) | MAOBGAAGSTP1BCHEMEN1 | |
| SCHEMBL5377289 | 0.75 | PTGER3 (0.51) | GAAGSTP1MEN1KMT2A | |
| SCHEMBL5377296 | 0.75 | PTGER3 (0.51) | GAAGSTP1MEN1KMT2A | |
| SCHEMBL5377062 | 0.74 | LTB4R (0.46) | PIN1GSTP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1228067-A1 | 5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGYLCEMIC AND HYPOLIPIDEMIC ACTIVITY | Takeda Chemical Industries, Ltd. (JP) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001038325-A1 | 5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-31 | — | — | WO | disclosed |