Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.40 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11451311 | 0.85 | TDP1 (0.46) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL8413080 | 0.77 | TDP1 (0.48) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL9060998 | 0.77 | TDP1 (0.48) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL6529410 | 0.75 | CYP11B1 (0.53) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL6530090 | 0.75 | TDP1 (0.46) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL8792548 | 0.75 | TDP1 (0.46) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL20683088 | 0.74 | TDP1 (0.48) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL8013907 | 0.74 | TDP1 (0.52) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL273486 | 0.74 | TDP1 (0.52) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL1939000 | 0.73 | TDP1 (0.44) | TDP1CYP11B1CYP11B2TNFHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0357061-B1 | Angiogenesis inhibitory agent | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-06-08 | — | — | EP | claimed |