Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3030830 | 0.74 | SIGMAR1 (0.69) | SIGMAR1ALDH1A1POLBLMNA | |
| SCHEMBL4419316 | 0.74 | ADRA1D (0.74) | ADRA1DADRA1AADRA1BACHE | |
| SCHEMBL242970 | 0.73 | SIGMAR1 (1.00) | SIGMAR1ACHEPOLBLMNA | |
| SCHEMBL1041303 | 0.73 | SIGMAR1 (1.00) | SIGMAR1ACHEPOLBLMNA | |
| SCHEMBL8188324 | 0.73 | SIGMAR1 (1.00) | SIGMAR1ACHEPOLBLMNA | |
| SCHEMBL2489199 | 0.73 | SIGMAR1 (1.00) | SIGMAR1ACHEPOLBLMNA | |
| SCHEMBL1415730 | 0.73 | SIGMAR1 (1.00) | SIGMAR1ACHEPOLBLMNA | |
| SCHEMBL576868 | 0.73 | SIGMAR1 (1.00) | SIGMAR1ACHEPOLBLMNA | |
| SCHEMBL2683476 | 0.72 | CASP3 (0.42) | ALDH1A1ALDH3A1POLBGAA | |
| SCHEMBL7986385 | 0.72 | ADRA1D (0.70) | ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748807-A1 | Derivatives of N-(1,4-diazabicyclo(2.2.2)-oct-2-yl)methyl benzamide, their preparation and their therapeutical use | SYNTHELABO (FR) | 1996-12-18 | — | — | EP | disclosed |