Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7496213 | 0.87 | RAB9A (0.43) | MEN1KMT2AKDM4EGAAMAPT | |
| SCHEMBL1961428 | 0.86 | CYP2D6 (0.43) | KMT2ATDP1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL31419413 | 0.67 | PTGS1 (0.44) | MEN1KMT2ATDP1ALDH1A1KDM4E | |
| SCHEMBL28150086 | 0.65 | PTGS1 (0.47) | MEN1KMT2ATDP1ALDH1A1KDM4E | |
| SCHEMBL1044416 | 0.64 | ALDH1A1 (0.50) | MEN1KMT2ATDP1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL28667324 | 0.63 | ALDH1A1 (0.49) | MEN1KMT2ATDP1ALDH1A1KDM4E | |
| Bromide SCHEMBL1178937 | 0.63 | ALDH1A1 (0.49) | MEN1KMT2ATDP1ALDH1A1KDM4E | |
| SCHEMBL13856724 | 0.60 | ALDH1A1 (1.00) | MEN1KMT2ATDP1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL30558881 | 0.60 | ALDH1A1 (0.45) | MEN1KMT2ATDP1ALDH1A1KDM4E | |
| SCHEMBL10074441 | 0.60 | HDAC1 (0.62) | MEN1KMT2ATDP1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0734386-B1 | PLATELET ACTIVATING FACTOR ANTAGONISTS: IMIDAZOPYRIDINE INDOLES | ABBOTT LAB (US) | 2002-02-06 | — | — | EP | disclosed |
| US-5486525-A | ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1996-01-23 | — | — | US | disclosed |