Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 8/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5724950 | 0.87 | FKBP1A (0.43) | TMEM97SIGMAR1ALDH1A1GFERHRH3 | |
| SCHEMBL5724804 | 0.80 | PREP (0.42) | ALDH1A1GFERTSHRL3MBTL1HRH3 | |
| SCHEMBL7564657 | 0.80 | GFER (0.45) | TMEM97SIGMAR1ALDH1A1GFERTSHR | |
| SCHEMBL5724709 | 0.74 | NPC1 (0.40) | ALDH1A1L3MBTL1LMNAHRH3 | |
| SCHEMBL22721972 | 0.73 | TMEM97 (0.56) | TMEM97SIGMAR1L3MBTL1FKBP1A | |
| SCHEMBL29540420 | 0.73 | TMEM97 (0.56) | TMEM97SIGMAR1L3MBTL1FKBP1A | |
| SCHEMBL22338396 | 0.72 | FKBP1A (0.64) | KDM4ELMNAPRCPFKBP1A | |
| SCHEMBL27195151 | 0.71 | SIGMAR1 (0.54) | TMEM97SIGMAR1FKBP1A | |
| SCHEMBL23485251 | 0.70 | FKBP1A (0.60) | KDM4ELMNAPRCPFKBP1A | |
| SCHEMBL28964198 | 0.69 | TSHR (0.52) | TMEM97SIGMAR1ALDH1A1GFERTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246810-A1 | PIPERIDINYLOXY AND PYRROLIDINYLOXYPHENYL OXAZOLIDINONES AS ANTIBACTERIALS | Ortho-McNeil Pharmaceutical, Inc. (US) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001046164-A1 | PIPERIDINYLOXY AND PYRROLIDINYLOXYPHENYL OXAZOLIDINONES AS ANTIBACTERIALS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-06-28 | — | — | WO | disclosed |