Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10992840 | 0.74 | MEN1 (0.49) | F2PRSS1CRBNDDB1MEN1 | |
| SCHEMBL9012682 | 0.71 | TSHR (0.46) | CTRB1CA1CA9ALDH1A1HPGD | |
| SCHEMBL7339250 | 0.71 | TSHR (0.46) | CTRB1CA1CA9ALDH1A1HPGD | |
| SCHEMBL982856 | 0.71 | TSHR (0.46) | CTRB1CA1CA9ALDH1A1HPGD | |
| SCHEMBL6009333 | 0.70 | F2 (0.41) | F2PRSS1CRBNDDB1MEN1 | |
| SCHEMBL18124767 | 0.68 | CYP2C19 (0.56) | CRBNDDB1CTRB1CA1CA9 | |
| SCHEMBL11027739 | 0.68 | F2 (0.36) | F2PRSS1CRBNDDB1MEN1 | |
| SCHEMBL7493544 | 0.67 | — | — | |
| SCHEMBL4700938 | 0.67 | CRBN (0.47) | F2PRSS1CRBNDDB1MEN1 | |
| SCHEMBL7379470 | 0.66 | MEN1 (0.48) | MEN1KMT2ACTRB1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090305239-A1 | Methods and compositions for determing a level of biologically active serum paraoxonase | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2009-12-10 | — | — | US | disclosed |
| EP-1915457-A2 | METHODS AND COMPOSITIONS FOR DETERMINING A LEVEL OF BIOLOGICALLY ACTIVE SERUM PARAOXONASE | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007020632-A2 | METHODS AND COMPOSITIONS FOR DETERMINING A LEVEL OF BIOLOGICALLY ACTIVE SERUM PARAOXONASE | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2007-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090305239-A1 | Methods and compositions for determing a level of biologically active serum paraoxonase | PON1, LPO, PNLIP | F2 523/4885PRSS1 128/4885CRBN 3721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.