SCHEMBL74937

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL941425	0.86	ALDH1A1 (0.46)	ALDH1A1GAAABCB1KMT2AMRGPRX4
	SCHEMBL12253327	0.81	ABCB1 (0.44)	ALDH1A1GAAABCB1KMT2AMRGPRX4
	SCHEMBL19645156	0.80	MRGPRX4 (0.35)	ALDH1A1GAAABCB1MRGPRX4ADRB2
	SCHEMBL6634297	0.80	ABCB1 (0.45)	ALDH1A1GAAABCB1KMT2AMRGPRX4
	SCHEMBL12216198	0.79	TYMS (0.46)	ALDH1A1GAAABCB1KMT2AMRGPRX4
	SCHEMBL19139258	0.79	ELANE (0.47)	ALDH1A1GAAABCB1ELANEMRGPRX4
	SCHEMBL14001892	0.78	KMT2A (0.38)	ALDH1A1KMT2AATMELANEKDM4E
	SCHEMBL7383485	0.77	ALDH1A1 (0.44)	ALDH1A1GAAABCB1KMT2AMRGPRX4
	SCHEMBL11805157	0.77	MRGPRX4 (0.52)	ALDH1A1GAAABCB1KMT2AMRGPRX4
	SCHEMBL12930759	0.77	TOP1 (0.56)	ALDH1A1GAAABCB1KMT2AMRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 460 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.