SCHEMBL7494032

SCHEMBL7494032

CNC(=O)C(=NOC)c1ccccc1CON=C(C)C(=NOC)c1ccc(Oc2cccc(C(F)(F)F)c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 7/20 0.47
MAPK14 Q16539 1/20 0.40
RXFP1 Q9HBX9 2/20 0.37
MAOB P27338 1/20 0.36
BTK Q06187 1/20 0.36
RAF1 P04049 1/20 0.36
GCGR P47871 1/20 0.36
KDR P35968 1/20 0.35
LTA4H P09960 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8544633 0.96 HIF1A (0.44) HIF1AMAPK14RXFP1MAOBBTK
SCHEMBL7498154 0.92 HIF1A (0.57) HIF1AMAPK14RXFP1MAOBGCGR
SCHEMBL7492706 0.89 HIF1A (0.42) HIF1AMAPK14RXFP1MAOBLTA4H
SCHEMBL7462688 0.85 HIF1A (0.51) HIF1AMAOBMAPT
SCHEMBL828172 0.83 HIF1A (0.52) HIF1ARXFP1
SCHEMBL123529 0.83 HIF1A (0.52) HIF1ARXFP1
SCHEMBL29765420 0.83 HIF1A (0.52) HIF1ARXFP1
SCHEMBL14141835 0.83 HIF1A (0.52) HIF1ARXFP1
SCHEMBL483559 0.83 HIF1A (0.52) HIF1ARXFP1
SCHEMBL30354029 0.83 HIF1A (0.52) HIF1ARXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6420423-B1 PESTICIDE FOR USE ON CEREALS, BEETS, FRUITS, BERRIES, AND BEANS; KILLS MITES, INSECTS, TERMITES, LICE, FLEAS, AND FUNGUS; TOLERATED WELL BE ANIMALS, PLANTS, AND FISH BAYER AKTIENGESELLSCHAFT (DE) 2002-07-16 US disclosed
EP-1207152-A2 Pesticides Bayer Aktiengesellschaft (DE) 2002-05-22 EP disclosed
US-5985921-A OXIDATION AND HYDROGENATION OF COMPOUNDS TO FORM INSECTICIDES AS AGROCHEMICALS NOVARTIS CORPORATION (US) 1999-11-16 US disclosed