Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 7/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7494032 | 0.96 | HIF1A (0.47) | HIF1AMAPK14RXFP1BTKMAOB | |
| SCHEMBL7492706 | 0.93 | HIF1A (0.42) | HIF1AMAPK14RXFP1MAOBPPARG | |
| SCHEMBL7462688 | 0.90 | HIF1A (0.51) | HIF1AMAOB | |
| SCHEMBL7498154 | 0.88 | HIF1A (0.57) | HIF1AMAPK14RXFP1MAOBGCGR | |
| SCHEMBL7498528 | 0.87 | HIF1A (0.39) | HIF1APPARG | |
| SCHEMBL7495777 | 0.86 | HIF1A (0.44) | HIF1A | |
| SCHEMBL7499090 | 0.85 | HIF1A (0.47) | HIF1AMAOBPPARG | |
| SCHEMBL7467255 | 0.84 | HIF1A (0.41) | HIF1AMAPK14PTPN2PTPN1PTPN11 | |
| SCHEMBL7467258 | 0.84 | HIF1A (0.41) | HIF1AMAPK14PTPN2PTPN1PTPN11 | |
| SCHEMBL7496684 | 0.84 | MAOB (0.48) | HIF1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865424-A1 | PESTICIDES | Novartis AG (CH) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020809-A1 | PESTICIDES | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |