SCHEMBL7494685

SCHEMBL7494685

CC[CH]Oc1ccccc1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 6/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41
SLC6A3 Q01959 1/20 0.41
MAPT P10636 3/20 0.40
TDP1 Q9NUW8 1/20 0.40
LMNA P02545 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
KCNH2 Q12809 1/20 0.38
HPGD P15428 3/20 0.37
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
TSHR P16473 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
PKM P14618 1/20 0.36
CXCL8 P10145 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10370306 0.84 ALDH1A1 (0.40) L3MBTL1TDP1LMNASMN1; SMN2TSHR
SCHEMBL27853372 0.82 ALDH1A1 (0.39) L3MBTL1SLC6A2SLC6A4SLC6A3MAPT
SCHEMBL27853319 0.77 SLC6A4 (0.44) L3MBTL1SLC6A2SLC6A4SLC6A3SMN1; SMN2
SCHEMBL9317193 0.77 TSHR (0.41) MAPTTDP1SMN1; SMN2HPGDNPC1
SCHEMBL5778963 0.77 CA1 (0.56) L3MBTL1TDP1LMNASMN1; SMN2TSHR
SCHEMBL9705392 0.76 MAOB (0.41) L3MBTL1SLC6A2SLC6A4SLC6A3MAPT
SCHEMBL7691212 0.76 TDP1 (0.47) L3MBTL1SLC6A2SLC6A4SLC6A3MAPT
SCHEMBL535467 0.76 LMNA (0.42) L3MBTL1SLC6A2SLC6A4SLC6A3MAPT
SCHEMBL1702501 0.75 CA2 (0.50) L3MBTL1MAPTTDP1LMNASMN1; SMN2
SCHEMBL4065849 0.75 ALDH1A1 (0.55) L3MBTL1MAPTTDP1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102471258-A 3-phenoxymethylpyrrolidine compounds THERAVANCE INC 2012-05-23 CN disclosed
EP-0760362-B1 DIAMINOMETHYLIDENE DERIVATIVE NISSHIN SEIFUN GROUP INC (JP) 2002-08-14 EP disclosed
EP-0760368-B1 PYRIMIDINE DERIVATIVES NISSHIN FLOUR MILLING CO (JP) 1999-07-28 EP disclosed
US-5753654-A GASTROINTESTINAL DISORDERS NISSHIN FLOUR MILLING CO., LTD. (JP) 1998-05-19 US disclosed
US-5736550-A TREATMENT OF GASTROINTESTINAL TRACT DISORDERS NISSHIN FLOUR MILLING CO., LTD. (JP) 1998-04-07 US disclosed
EP-0760362-A1 NOVEL DIAMINOMETHYLIDENE DERIVATIVE NISSHIN FLOUR MILLING CO., LTD. (JP) 1997-03-05 EP disclosed
EP-0760368-A1 NOVEL PYRIMIDINE DERIVATIVE NISSHIN FLOUR MILLING CO., LTD. (JP) 1997-03-05 EP disclosed
EP-0136702-B1 CYCLOHEXENOL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN COMBATING UNDESIRABLE PLANT GROWTH BASF Aktiengesellschaft (DE) 1990-05-09 EP disclosed
US-4895587-A Haloacetamide compounds, process for production thereof, and use thereof as herbicide TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1990-01-23 US disclosed
EP-0311907-A2 3-Substituted pyridines and fungicides containing them BASF Aktiengesellschaft (DE) 1989-04-19 EP disclosed
EP-0189774-B1 PROCESS FOR PRODUCTION OF N,N-DISUBSTITUTED CARBOXYLIC ACID AMIDES TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1989-04-12 EP disclosed
EP-0206251-B1 HALOACETAMIDE COMPOUNDS, PROCESS FOR PRODUCTION THEREOF, AND USE THEREOF AS HERBICIDE TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1988-09-07 EP disclosed
US-4761172-A PRE- AND POSTEMERGENCE BASF AKTIENGESELLSCHAFT (DE) 1988-08-02 US disclosed
EP-0206251-A1 Haloacetamide compounds, process for production thereof, and use thereof as herbicide TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1986-12-30 EP disclosed
EP-0189774-A1 Process for production of N,N-disubstituted carboxylic acid amides TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1986-08-06 EP disclosed
EP-0136702-A2 Cyclohexenol derivatives, process for their preparation and their use in combating undesirable plant growth BASF Aktiengesellschaft (DE) 1985-04-10 EP disclosed