Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 9/20 | 0.37 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.37 |
| ▸ | MLNR | O43193 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7500897 | 1.00 | GHSR (0.39) | GHSRHSD11B1AADATMLNRKMT2A | |
| SCHEMBL7499026 | 0.83 | KMT2A (0.48) | AADATKMT2ALMNAMAPTMEN1 | |
| SCHEMBL7499021 | 0.83 | KMT2A (0.48) | AADATKMT2ALMNAMAPTMEN1 | |
| SCHEMBL7501902 | 0.75 | FKBP1A (0.46) | AADATMAPT | |
| SCHEMBL7498358 | 0.73 | UCHL1 (0.39) | HSD11B1AADAT | |
| SCHEMBL7506786 | 0.70 | POLQ (0.39) | LMNAMAPT | |
| SCHEMBL7495012 | 0.69 | PDE4B (0.46) | LMNA | |
| SCHEMBL7505924 | 0.67 | UCHL1 (0.42) | KMT2AMAPTMEN1 | |
| SCHEMBL4078297 | 0.66 | MAT2A (0.47) | KMT2ALMNAMAPT | |
| SCHEMBL4084126 | 0.66 | MAT2A (0.47) | KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826673-B1 | ACETAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO (JP) | 2002-11-20 | — | — | EP | disclosed |
| US-5972946-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0826673-A1 | ACETAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-03-04 | — | — | EP | disclosed |