Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.59 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2936345 | 0.87 | KMT2A (0.60) | ROCK2ROCK1KMT2AMEN1HPGD | |
| SCHEMBL6289035 | 0.86 | HPGD (0.58) | ROCK2ROCK1KMT2AMEN1HPGD | |
| SCHEMBL6289034 | 0.86 | HPGD (0.58) | ROCK2ROCK1KMT2AMEN1HPGD | |
| SCHEMBL885000 | 0.85 | MTNR1A (0.71) | KMT2AMEN1MTNR1AMTNR1BHPGD | |
| SCHEMBL1009815 | 0.84 | MTNR1A (0.75) | MTNR1AMTNR1B | |
| SCHEMBL13853507 | 0.84 | HIF1A (0.56) | ROCK2ROCK1KMT2AMEN1HPGD | |
| SCHEMBL7318332 | 0.80 | ALDH1A1 (0.56) | ROCK2ROCK1KMT2AMEN1HPGD | |
| SCHEMBL5723907 | 0.80 | MTNR1A (0.56) | ROCK2MTNR1AMTNR1BALDH1A1HIF1A | |
| SCHEMBL7000552 | 0.79 | KDM4E (0.69) | KMT2AMEN1ALDH1A1ATMKDM4E | |
| SCHEMBL5963101 | 0.78 | KMT2A (0.65) | KMT2AMEN1ALDH1A1HIF1AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187613-A4 | AMIDE SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES CO (US) | 2002-07-24 | — | — | EP | claimed |
| EP-1187613-A1 | AMIDE SUBSTITUTED IMIDAZOQUINOLINES | 3M Innovative Properties Company (US) | 2002-03-20 | — | — | EP | claimed |
| WO-2000076505-A1 | AMIDE SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-12-21 | — | — | WO | claimed |