Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | APLNR | P35414 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL284141 | 0.85 | APLNR (0.55) | GAAAPLNRALDH1A1MEN1KMT2A | |
| SCHEMBL1717954 | 0.81 | APLNR (0.48) | GAAAPLNRALDH1A1MEN1KMT2A | |
| SCHEMBL11525177 | 0.80 | MEN1 (0.56) | GAAAPLNRALDH1A1MEN1KMT2A | |
| SCHEMBL14510768 | 0.80 | GAA (0.49) | GAAAPLNRALDH1A1MEN1KMT2A | |
| SCHEMBL9923753 | 0.79 | GAA (0.40) | GAAAPLNRMEN1KMT2ACA1 | |
| SCHEMBL24514107 | 0.78 | APLNR (0.50) | GAAAPLNRALDH1A1MEN1KMT2A | |
| SCHEMBL11971386 | 0.77 | APLNR (0.46) | GAAAPLNRALDH1A1MEN1KMT2A | |
| SCHEMBL19273270 | 0.76 | APLNR (0.48) | GAAAPLNRALDH1A1MEN1KMT2A | |
| SCHEMBL1935332 | 0.76 | APLNR (0.48) | GAAAPLNRALDH1A1MEN1KMT2A | |
| SCHEMBL8520807 | 0.75 | APLNR (0.47) | GAAAPLNRMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760370-B1 | NOVEL CARBAPENEM DERIVATIVES | MEIJI SEIKA CO (JP) | 2002-08-07 | — | — | EP | disclosed |
| US-5990101-A | Carbapenem derivatives | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1999-11-23 | — | — | US | disclosed |
| EP-0760370-A1 | NOVEL CARBAPENEM DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-03-05 | — | — | EP | disclosed |