SCHEMBL17770569

SCHEMBL17770569

COc1ccccc1C(=O)c1ccccc1Cl

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.60
KMT2A Q03164 1/20 0.60
HPGD P15428 2/20 0.59
RAB9A P51151 2/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
MAPK14 Q16539 2/20 0.56
MAPK13 O15264 1/20 0.56
MAPK12 P53778 1/20 0.56
MAPK11 Q15759 1/20 0.56
CES2 O00748 2/20 0.54
CES1 P23141 2/20 0.54
CTSD P07339 1/20 0.51
CNR2 P34972 1/20 0.50
POLB P06746 1/20 0.49
ALOX15 P16050 1/20 0.49
HSD17B10 Q99714 1/20 0.49
RECQL P46063 1/20 0.49
STAT3 P40763 1/20 0.49
ALDH1A1 P00352 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29658169 0.88 CTSD (0.62) LMNARAB9ASMN1; SMN2CTSDCNR2
SCHEMBL322168 0.88 CTSD (0.62) LMNARAB9ASMN1; SMN2CTSDCNR2
SCHEMBL27789892 0.86 CTSD (0.60) LMNARAB9ASMN1; SMN2CTSDCNR2
SCHEMBL13798207 0.85 RECQL (0.62) LMNAKMT2AHPGDRAB9ASMN1; SMN2
SCHEMBL31186154 0.85 MAPK13 (0.60) LMNAKMT2ARAB9ASMN1; SMN2MAPK14
SCHEMBL9566962 0.85 MAPK14 (0.62) LMNAKMT2AHPGDRAB9ASMN1; SMN2
SCHEMBL10711606 0.85 LMNA (0.57) LMNAKMT2AHPGDRAB9ASMN1; SMN2
SCHEMBL11577282 0.84 KMT2A (0.63) LMNAKMT2AHPGDRAB9ASMN1; SMN2
SCHEMBL11576124 0.84 MAPK13 (0.58) LMNAKMT2AHPGDRAB9AMAPK14
SCHEMBL8668642 0.84 ALDH1A1 (0.68) LMNAKMT2AHPGDRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110066479-A A kind of preparation method of anti-corrosion and high strength non-slip mat 赵玲萍 2019-07-30 CN disclosed
EP-3221393-A1 STABILIZER COMPOSITIONS AND METHODS FOR USING SAME FOR PROTECTING ORGANIC MATERIALS FROM UV LIGHT AND THERMAL DEGRADATION Cytec Industries Inc. (US) 2017-09-27 EP disclosed
WO-2016081823-A1 STABILIZER COMPOSITIONS AND METHODS FOR USING SAME FOR PROTECTING ORGANIC MATERIALS FROM UV LIGHT AND THERMAL DEGRADATION CYTEC INDUSTRIES INC. (US) 2016-05-26 WO disclosed