Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.41 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.41 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.41 |
| ▸ | CACNG7 | P62955 | 2/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.41 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.41 |
| ▸ | CACNG1 | Q06432 | 2/20 | 0.41 |
| ▸ | CACNB2 | Q08289 | 2/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8805468 | 0.90 | KDM4E (0.36) | MAPTSMN1; SMN2POLBLMNAKDM4E | |
| SCHEMBL7484252 | 0.89 | MAPT (0.49) | CYP2C9RECQLMAPTKMT2ACACNB4 | |
| SCHEMBL7494813 | 0.89 | MAPT (0.44) | CYP2C9RECQLMAPTKMT2ACACNB4 | |
| SCHEMBL8575723 | 0.85 | CYP2C9 (0.41) | CYP2C9RECQLMAPTKMT2ACACNB4 | |
| Diethylamine SCHEMBL7495295 | 0.82 | CYP2C9 (0.50) | CYP2C9RECQLMAPTKMT2ACACNB4 | |
| SCHEMBL7485972 | 0.79 | MAPT (0.53) | CYP2C9MAPTKMT2ACACNB4CACNA1A | |
| SCHEMBL7685688 | 0.78 | ADORA1 (0.46) | CYP2C9RECQLMAPTKMT2ACACNB4 | |
| SCHEMBL7488242 | 0.77 | MAPT (0.53) | CYP2C9RECQLMAPTKMT2ACACNB4 | |
| SCHEMBL7485921 | 0.74 | SLC10A2 (0.48) | MAPTCACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL7490064 | 0.74 | POLB (0.44) | CYP2C9RECQLMAPTKMT2ACACNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791000-B1 | THIENOPYRIDINE OR THIENOPYRIMIDINE DERIVATIVES AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-10-02 | — | — | EP | disclosed |